Connection Between Periodontal Disease and Alzheimer's

Periodontal disease, also known as gum disease, is a chronic inflammatory disease that affects the gums and supporting structures of the teeth. It is one of the most common chronic diseases in the world, affecting up to 50% of adults.

Alzheimer's disease is a neurodegenerative disease that causes progressive cognitive decline. It is the most common form of dementia, affecting over 6 million people in the United States.

Research has shown that there is a connection between periodontal disease and Alzheimer's disease. People with periodontal disease are more likely to develop Alzheimer's disease, and the severity of periodontal disease is associated with the severity of Alzheimer's disease.

There are a number of possible mechanisms by which periodontal disease may contribute to the development of Alzheimer's disease. One possibility is that the inflammation caused by periodontal disease can trigger inflammation in the brain. Inflammation is known to play a role in the development of Alzheimer's disease.

Another possibility is that bacteria from the mouth can travel to the brain and contribute to the development of Alzheimer's disease. Bacteria have been found in the brains of people with Alzheimer's disease, and these bacteria are similar to the bacteria that cause periodontal disease.

Finally, periodontal disease may contribute to the development of Alzheimer's disease by damaging the blood-brain barrier. The blood-brain barrier is a protective barrier that prevents harmful substances from entering the brain. Damage to the blood-brain barrier can allow harmful substances, such as bacteria and inflammatory proteins, to enter the brain and contribute to the development of Alzheimer's disease.

Here is a summary of some of the evidence that supports a connection between periodontal disease and Alzheimer's disease:

A study of over 15,000 people found that those with periodontal disease were more likely to develop Alzheimer's disease than those without periodontal disease.

Another study found that people with severe periodontal disease were more likely to develop Alzheimer's disease than those with mild or no periodontal disease.

A study of over 5,000 people found that those with periodontal disease were more likely to have amyloid plaques and tau tangles in their brains, which are two hallmarks of Alzheimer's disease.

A study of over 1,000 people found that those with periodontal disease had a higher risk of developing cognitive decline over time.

It is important to note that these studies do not prove that periodontal disease causes Alzheimer's disease. However, they do provide strong evidence that there is a connection between the two diseases.

More research is needed to understand the mechanisms by which periodontal disease may contribute to the development of Alzheimer's disease. However, the evidence suggests that taking care of your teeth and gums may be one way to reduce your risk of developing Alzheimer's disease.

What can you do to protect your brain health?

There are a number of things you can do to protect your brain health, including:

Taking care of your teeth and gums

Eating a healthy diet

Exercising regularly

Getting enough sleep

Managing stress

If you have periodontal disease, it is important to see a dentist or periodontist for treatment. Treatment for periodontal disease can help to reduce inflammation and prevent tooth loss.

By taking care of your teeth and gums and following the other tips above, you can help protect your brain health and reduce your risk of developing Alzheimer's disease.

Resource

https://www.dentistryiq.com/dentistry/pathology/article/14201185/evidence-mounts-that-periodontal-disease-is-connected-to-alzheimers